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Extensive scientific research has shown that Lyprinol PCSO-524® is extremely beneficial in aiding and/or treating osteoarthritis, rheumatoid arthritis and asthma (including exercise-induced asthma). This natural supplement, derived from the oil of the New Zealand green-lipped mussel (Perna canaliculus) contains a host of omega 3 PUFAs (polyunsaturated fatty acids) that work together to relieve pain and inflammation - both of which are presenting symptoms in all three these conditions. Lyprinol PCSO-524® contains no protein and is therefore, also suitable for people who suffer from seafood and shellfish allergies. Nationwide delivery. 


  • Safe, natural alternative to non-steroidal anti-inflammatories (NSAIDs) without the side-effects
  • Made from the oil of the New Zealand Perna canaliculus (green-lipped mussel)
  • Rich in omega 3 PUFAs, especially ETA and OTA (which are not found in fish oils) and furan acid
  • Shown to reduce swelling and Inflammation-induced pain by 89%
  • Increases mobility
  • Acts as an inflammatory antagonist in asthma
  • Contains no protein, making it safe for people with seafood allergies

What is Lyprinol PCSO-524®?

The launch of Lyprinol PCSO-524® in SA, now offers a natural therapy for people suffering from osteoarthritis, rheumatoid arthritis and asthma. It has been shown to be more effective than certain non-steroidal anti-inflammatory drugs (NSAIDs) while exhibiting none of the side-effects normally experienced during NSAID treatment. One study undertaken at the University of Queensland showed that Lyprinol PCSO-524® outperformed Indomethacin & Ibuprofen by 2:1. Subsequent trials showed that Lyprinol PCSO-524® was 175 times more potent than salmon oil and that it was 200 times more effective than flax oil in controlling arthritic joint swelling.

Lyprinol PCSO-524® is a natural marine extract from the oil of the New Zealand green-lipped mussel (Perna canaliculus) and is the most studied natural alternative known to provide relief from inflammatory pain and asthmatic symptoms. Lyprinol PCSO-524® is the only green-lipped mussel extract that is prepared by supercritical fluid (CO2) extraction. This retains the essential PUFAs, leaves no chemical solvent residues and removes the protein that causes shellfish allergies.

Clinical research has shown that Lyprinol PCSO-524 is the only marine or plant life that has a unique combination of 91 PUFAs (polyunsaturated fatty acids), including sterol esters, triglycerides, free fatty acids, sterols and polar lipids2.


Fighting inflammation is the omega 3 PUFA’s (active ingredient of Lyprinol PCSO-524®) main function. This is crucial, as so many life-threatening and debilitating diseases are caused by inflammation. These include asthma, rheumatoid arthritis and heart diseases, such as heart attacks, atherosclerosis, strokes (studies have shown a reduction of up to 27%) and arrhythmia (irregular heart rhythm). In fact, The South African Heart Foundation now recommends the use of omega 3 to prevent heart disease and improve the immune system.

What makes Lyprinol PCSO-524® particularly effective in fighting inflammation is the presence of the omega 3 PUFAs, eicosatetranoic acid (ETA), octadecatetranoic acid (OTA) and the rarely-found furan acid, which is also potent at scavenging free radicals.

Together, this exceptional blend of PUFAs is extremely effective in blocking the production of pro-inflammatory enzymes such as 5-lipoxygenase (5-LOX) and the cyclooxygenases (COX-1 + COX-2) enzymes that produce broncho-constricting leukotrienes and prostaglandins, which cause inflammatory-based diseases such as osteoarthritis and rheumatoid arthritis. A large body of research exists that shows how these omega 3 PUFAs, reduced joint tenderness, pain, morning stiffness and improved grip ability


A collaborative study was conducted by researchers from the Professor Dr. Baum Institute in Cologne, Germany and the Australian National University in Canberra, Australia to ascertain the effectiveness of Lyprinol PCSO-524® on DOMS (delayed onset muscle soreness) after a 30 km training run. The subjects were all males between the ages of 30 and 60. The symptoms of DOMS include pain, restricted movement, less strength, and some swelling. They found that the group who had received Lyprinol PCSO-524® experienced less DOMS and lower post-run CK (Creatine Kinase - a contributor to fibre deterioration) concentrations. The lower incidence of DOMS was more notable in less experienced runners. They concluded that Lyprinol PCSO-524® would be an excellent supplement for older runners to help them endure less DOMS and to recover faster from muscle-induced stress.


Lyprinol PCSO-524® also helps asthmatics as it inhibits the formation of bronchoconstricting leukotrienes. These leukotrienes are partly responsible for the production of excessive mucous and the constriction of the bronchial airways. A study conducted at the Pavlov Medical University Hospital in St Petersburg, found the following results after only 56 days. There was a 50% reduction in rescue medicine, a 65% reduction in exhaled H2O2 (hydrogen peroxide), a significant reduction in chest tightness and the incidence of night-time attacks. They concluded that Lyprinol PCSO-524® was an effective means of treating inflammation in the airways. Research has also shown that Lyprinol PCSO-524®’s anti-inflammatory properties are effective in treating exercise-induced bronchoconstriction (EIB).

Heart Health

Because Lyprinol PCSO-524® is so rich in omega 3 it can benefit your heart as well. It can:

  • Regulate heart beat
  • Prevent clots and inflammation of the blood vessels
  • Reduce triglycerides (the main element of fats and oils in the blood)
  • Decrease the growth of plaque allowing the blood to flow without restriction
  • Lower blood pressure



Recent studies are showing that omega 3 can help with depression. These studies show that there is a direct correlation between low omega 3 levels and depression, hostility and impulsive behaviour. Additionally, they found that high levels of EPA and DHA increased the volume of brain matter that controls depression and moods.

Dr Hibbeln, from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) states that: “The strongest evidence was found for managing major depressive symptoms, with the effect of omega-3s being at least as great, if not greater than, antidepressant medications.”

Various other clinical trials that ranged from children to adults, showed omega 3’s significance in managing different forms of depression that included bipolar, unipolar, menopausal and major depression.


New evidence is emerging that omega 3s can play a role in preventing certain types of cancer in those who are at risk, as well as aiding those who are suffering from either cancer or the side effects of treatment. These include breast and prostate cancer. One very recent study conducted at Washington State University was able to show that the fatty acids bind with a receptor called FFA4 (free fatty acid receptor 4) and in doing so, suppresses the growth of prostate cancer cells.

What else

Sufficient levels of omega 3 prevent exhaustion, digestive complications, lack of concentration, aching joints, skin problems and brittle hair and nails.

The PUFA, Docosahexaenoic acid (DHA), also plays an essential role in the development of mental abilities in children and reducing age induced memory loss. DHA also helps in building bone density and is therefore, helpful for treating and preventing osteoporosis.

Every product has a story behind it… and Lyprinol is no different… or maybe it is?! Lyprinol is the trade name for an oily extract of the Green Lipped Mussel, which is found in the pristine waters around the coast of New Zealand. It was noticed that the Maoris, the indigenous people of this land, living away from the coast developed different forms of arthritis. Yet, the Maoris living at the coast didn’t suffer similarly! The medical fraternity were baffled by this phenomenon. Then they analysed the food that the Maoris living by the coast ate… and discovered that the Green Lipped Mussel was the reason for the coastal Maori community not suffering from these debilitating ailments. Through research it was established that the Green Lipped Mussel contained many unique fatty acids (Omega 3) that worked against the development of arthritic conditions such as rheumatoid and osteoarthritis and as a result people consuming Green Lipped Mussel were helped with this debilitating condition. In the early days, so as to help people living beyond the boundaries of consuming fresh Green Lipped Mussel, the mussel was dried and then ground up and filled into capsules. The main disadvantage of this way of taking Green Lipped Mussel is that the amount of fatty acids per capsule was unknown as the different seasons of harvesting the mussel affected the fatty acid content. Eventually, new technology was developed and the oily fatty acids were extracted by a patented method, called super critical extraction, which ensures that an exact measured dose of these fatty acids could be taken in a capsule… This was the birth of Lyprinol and its success has been demonstrated worldwide with more studies on this natural product than on in any other natural product. It maybe challenged that Extra Virgin Olive Oil (EVOO) has been equally studied for its qualities in supporting human health, and there is no question that EVOO should be included daily in the human diet along with Lyprinol for its unique qualities. There is lots of information on the internet to the many virtues of Lyprinol, including keeping your immune system strong, improved heart health, and help against delayed onset muscle soreness (DOMS). NOTE: Results of taking Lyprinol will vary from person to person. The international growth of Lyprinol has been mainly due to personal recommendation. In South Africa, the number of satisfied customers keeps on growing… since it’s regular availability for over ten years now.

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